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Drug Name Zolbetuximab
Trade Name
Synonyms IMAB362|Claudiximab
Drug Descriptions

Zolbetuximab (IMAB362) is a monoclonal antibody that binds to the tight junction molecule CLDN18.2, thereby blocking proliferation of tumor cells (PMID: 23900716, PMID: 26811601, PMID: 31240302).

CAS Registry Number 1496553-00-4
NCIT ID C85475


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + Oxaliplatin + Zolbetuximab Capecitabine Oxaliplatin Zolbetuximab 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Zolbetuximab Fluorouracil Leucovorin Oxaliplatin Zolbetuximab 0 2
Gemcitabine + Nab-paclitaxel + Zolbetuximab Gemcitabine Nab-paclitaxel Zolbetuximab 0 1
Pembrolizumab + Zolbetuximab Pembrolizumab Zolbetuximab 0 1
Zolbetuximab Zolbetuximab 0 1

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