Drug Detail


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Drug Name Andecaliximab
Trade Name
Synonyms GS-5745
Drug Descriptions

Andecaliximab (GS-5745) is a monoclonal antibody that binds to and inhibits matrix metalloproteinase 9 (MMP-9), which may lead to inhibition of matrix degradation and tumor metastasis (PMID: 25961845, PMID: 29691300).

CAS Registry Number 1518996-49-0
NCIT ID C105803


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Andecaliximab Andecaliximab 0 2
Andecaliximab + Bevacizumab Andecaliximab Bevacizumab 0 1
Andecaliximab + Fluorouracil + Leucovorin + Oxaliplatin Andecaliximab Fluorouracil Leucovorin Oxaliplatin 0 0
Andecaliximab + Nivolumab Andecaliximab Nivolumab 0 1

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