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Drug Name CIMAvax-EGF
Trade Name
Synonyms CimaVax|CimaVax Vaccine|CIMAvax EGF
Drug Descriptions

CIMAvax-EGF (EGF vaccine) is a cancer vaccine composed of EGF linked to the carrier protein Neisseria meningitidis-derived P64k, which induces an immune response against EGF, resulting in decreased EGF expression and has potential antitumor activity (PMID: 26927662, PMID: 27566188).

CAS Registry Number NA
NCIT ID C70674


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Cetuximab + CIMAvax-EGF + Leucovorin Bevacizumab CIMAvax-EGF Cetuximab Leucovorin 0 1
Bevacizumab + CIMAvax-EGF + Fluorouracil + Leucovorin + Oxaliplatin Bevacizumab CIMAvax-EGF Fluorouracil Leucovorin Oxaliplatin 0 1
Cetuximab + CIMAvax-EGF + Fluorouracil + Irinotecan + Leucovorin CIMAvax-EGF Cetuximab Fluorouracil Irinotecan Leucovorin 0 1
Cetuximab + CIMAvax-EGF + Fluorouracil + Oxaliplatin CIMAvax-EGF Cetuximab Fluorouracil Oxaliplatin 0 1
CIMAvax-EGF + Nivolumab CIMAvax-EGF Nivolumab 0 1

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