Drug Detail


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Drug Name Bevacizumab-awwb
Trade Name Mvasi
Synonyms ABP 215
Drug Descriptions

Mvasi (bevacizumab-awwb) is a biosimilar to the anti-VEGF antibody Avastin (bevacizumab), which binds to and inhibits VEGF, resulting in decreased tumor growth and angiogenesis (PMID: 29743182). Mvasi (bevacizumab-awwb) is FDA approved for use in combination with chemotherapy in colorectal cancer, in combination with carboplatin and paclitaxel in non-squamous non-small cell lung cancer, in glioblastoma, in combination with interferon-alfa in renal cell carcinoma, and in combination with paclitaxel and cisplatin or topotecan in cervical cancer (FDA.gov).

DrugClasses VEGF Antibody 11
CAS Registry Number NA


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab-awwb Bevacizumab-awwb 0 1
Bevacizumab-awwb + Carboplatin + Paclitaxel Bevacizumab-awwb Carboplatin Paclitaxel 0 0
Bevacizumab-awwb + Fluorouracil + Irinotecan + Sotorasib Bevacizumab-awwb Fluorouracil Irinotecan Sotorasib 0 1
Bevacizumab-awwb + Fluorouracil + Oxaliplatin + Sotorasib Bevacizumab-awwb Fluorouracil Oxaliplatin Sotorasib 0 1
Bevacizumab-awwb + Sotorasib Bevacizumab-awwb Sotorasib 0 1

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