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Drug Name MVT-5873
Trade Name
Synonyms HuMab 5B1|HuMab-5B1|BNT321
Drug Descriptions

MVT-5873 (HuMab-5B1) is an IgG1 antibody that binds to the sialyl Lewis A epitope of CA19-9, which may result in antitumor activity including tumor growth inhibition (Cancer Res 2016;76(24 Suppl):Abstract nr A73, PMID: 32399263).

CAS Registry Number 2101410-19-7
NCIT ID C125900


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fluorouracil + Irinotecan + Leucovorin + MVT-5873 + Oxaliplatin Fluorouracil Irinotecan Leucovorin MVT-5873 Oxaliplatin 0 1
Gemcitabine + MVT-5873 + Nab-paclitaxel Gemcitabine MVT-5873 Nab-paclitaxel 0 0
MVT-1075 + MVT-5873 MVT-1075 MVT-5873 0 1
MVT-5873 MVT-5873 0 2

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