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Drug Name JNJ-64457107
Trade Name
Synonyms ADC-1013|Mitazalimab|JNJ 7107
Drug Descriptions

JNJ-64457107 (mitazalimab) is a CD40 agonist that may lead to a T-cell dependent antitumor response, potentially resulting in tumor growth inhibition (PMID: 25316820, PMID: 30664811).

DrugClasses CD40 Antibody 14
CAS Registry Number 2055640-86-1
NCIT ID C121538


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fluorouracil + Irinotecan + JNJ-64457107 + Leucovorin + Oxaliplatin Fluorouracil Irinotecan JNJ-64457107 Leucovorin Oxaliplatin 0 1
JNJ-64457107 JNJ-64457107 0 2

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