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Drug Name Sapitinib
Trade Name
Synonyms AZD8931|AZD89311
Drug Descriptions

Sapitinib (AZD8931) binds to and inhibits the ERBB family members EGFR, ERBB2 (HER2), and ERBB3, which may lead to decreased tumor cell proliferation and increased apoptosis (PMID: 20145185).

DrugClasses EGFR Inhibitor (Pan) 45 HER2 Inhibitor 22 HER3 Inhibitor 2

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Sapitinib Atezolizumab Sapitinib 0 0
Cisplatin + Fluorouracil + Sapitinib Cisplatin Fluorouracil Sapitinib 1 0
Paclitaxel + Sapitinib Paclitaxel Sapitinib 0 0
Sapitinib Sapitinib 18 0


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