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Drug Name Telisotuzumab vedotin
Trade Name
Synonyms ABBV-399|Teliso-V
Drug Descriptions

Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate comprising a MET-targeted antibody linked to MMAE, which delivers the cytotoxic agent to MET expressing tumor cells, resulting in cell death (PMID: 27573171, PMID: 32127466).

DrugClasses MET Antibody 28
CAS Registry Number 1781223-80-0
NCIT ID C118571

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Telisotuzumab vedotin Bevacizumab Telisotuzumab vedotin 0 1
Carboplatin + Telisotuzumab vedotin Carboplatin Telisotuzumab vedotin 0 1
Cetuximab + Telisotuzumab vedotin Cetuximab Telisotuzumab vedotin 0 1
Erlotinib + Telisotuzumab vedotin Erlotinib Telisotuzumab vedotin 0 1
Osimertinib + Telisotuzumab vedotin Osimertinib Telisotuzumab vedotin 0 0
Telisotuzumab vedotin Telisotuzumab vedotin 0 6


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