Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Telisotuzumab vedotin
Trade Name
Synonyms ABBV-399|Teliso-V
Drug Descriptions

Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate comprising a MET-targeted antibody linked to MMAE, which delivers the cytotoxic agent to MET expressing tumor cells, resulting in cell death (PMID: 27573171, PMID: 32127466).

DrugClasses MET Antibody 29
CAS Registry Number 1781223-80-0
NCIT ID C118571


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Telisotuzumab vedotin Bevacizumab Telisotuzumab vedotin 0 1
Carboplatin + Telisotuzumab vedotin Carboplatin Telisotuzumab vedotin 0 1
Cetuximab + Telisotuzumab vedotin Cetuximab Telisotuzumab vedotin 0 1
Erlotinib + Telisotuzumab vedotin Erlotinib Telisotuzumab vedotin 0 1
Osimertinib + Telisotuzumab vedotin Osimertinib Telisotuzumab vedotin 0 0
Telisotuzumab vedotin Telisotuzumab vedotin 0 6

Additional content available in CKB BOOST