Drug Detail


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Drug Name Emactuzumab
Trade Name
Synonyms RG7155|RO5509554
Drug Descriptions

Emactuzumab (RG7155) is a monoclonal antibody that inhibits dimerization of CSF1R, resulting in decreased ligand-dependent and ligand-independent signaling, thereby potentially leading to reduced tumor growth (PMID: 24898549, PMID: 32575160, PMID: 31114846).

DrugClasses CSF1R Inhibitor 28
CAS Registry Number 1448221-67-7
NCIT ID C125548


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Emactuzumab Atezolizumab Emactuzumab 0 3
Bevacizumab + Emactuzumab + Paclitaxel Bevacizumab Emactuzumab Paclitaxel 0 1
Emactuzumab Emactuzumab 0 2
Emactuzumab + Paclitaxel Emactuzumab Paclitaxel 0 1
Emactuzumab + Selicrelumab Emactuzumab Selicrelumab 0 1

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