Drug Detail


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Drug Name Selicrelumab
Trade Name
Synonyms RO7009789|CP 870,893
Drug Descriptions

Selicrelumab (RO7009789) is a monoclonal antibody to TNFRSF5 (CD40), which mimics the binding of the ligand, CD40LG (CD40L), to stimulate proliferation of T-cells and enhance an anti-tumor response (PMID: 26386124).

DrugClasses CD40 Antibody 14
CAS Registry Number 1622140-49-1
NCIT ID C119740


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Selicrelumab Atezolizumab Bevacizumab Selicrelumab 0 1
Atezolizumab + Gemcitabine + Nab-paclitaxel + Selicrelumab Atezolizumab Gemcitabine Nab-paclitaxel Selicrelumab 0 0
Bevacizumab + Selicrelumab Bevacizumab Selicrelumab 0 1
Emactuzumab + Selicrelumab Emactuzumab Selicrelumab 0 1
RO5520985 + Selicrelumab RO5520985 Selicrelumab 0 1
Selicrelumab Selicrelumab 0 1

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