Drug Detail


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Drug Name Sintilimab
Trade Name
Synonyms IBI308|Tyvyt
Drug Descriptions

Sintilimab (IBI308) is a monoclonal antibody that targets PD-1 (PDCD1), potentially resulting in enhanced anti-tumor immune response (PMID: 29300693, PMID: 29900038, PMID: 32656988).

DrugClasses Immune Checkpoint Inhibitor 148 PD-L1/PD-1 antibody 117
CAS Registry Number 2072873-06-2
NCIT ID C132992


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anlotinib + Cisplatin + Nab-paclitaxel + Sintilimab Anlotinib Cisplatin Nab-paclitaxel Sintilimab 0 0
Anlotinib + Sintilimab Anlotinib Sintilimab 1 0
Bevacizumab + Sintilimab Bevacizumab Sintilimab 0 0
Cisplatin + Fluorouracil + Sintilimab Cisplatin Fluorouracil Sintilimab 0 1
Cisplatin + Nab-paclitaxel + Sintilimab Cisplatin Nab-paclitaxel Sintilimab 0 0
Cisplatin + Paclitaxel + Sintilimab Cisplatin Paclitaxel Sintilimab 0 1
Dabrafenib + Sintilimab + Trametinib Dabrafenib Sintilimab Trametinib 0 0
Fluorouracil + Irinotecan + Leucovorin + Sintilimab Fluorouracil Irinotecan Leucovorin Sintilimab 0 0
Fruquintinib + Sintilimab Fruquintinib Sintilimab 0 0
IBI110 + Sintilimab IBI110 Sintilimab 0 1
IBI310 + Sintilimab IBI310 Sintilimab 0 0
LY3537982 + Sintilimab LY3537982 Sintilimab 0 1
Nab-paclitaxel + Sintilimab Nab-paclitaxel Sintilimab 0 0
Sintilimab Sintilimab 0 4

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