Drug Detail


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Drug Name Tivantinib
Trade Name
Synonyms ARQ197|ARQ 197|ARQ-197
Drug Descriptions

Tivantinib (ARQ197) inhibits MET and may have antimitotic activity, potentially resulting in decreased tumor cell proliferation and reduced tumor growth (PMID: 29924867, PMID: 28246274).

DrugClasses MET Inhibitor 58
CAS Registry Number 905854-02-6
NCIT ID C62437


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Tivantinib Afatinib Tivantinib 0 0
Bevacizumab + Tivantinib Bevacizumab Tivantinib 0 1
Cetuximab + Tivantinib Cetuximab Tivantinib 0 0
Pegfilgrastim + Tivantinib + Topotecan Pegfilgrastim Tivantinib Topotecan 0 1
Temsirolimus + Tivantinib Temsirolimus Tivantinib 0 1
Tivantinib Tivantinib 0 3

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