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Drug Name GEN-1
Trade Name
Synonyms phIL-12-005|GEN1|GEN 1
Drug Descriptions

GEN-1 comprises a plasmid engineered to express IL-12 encapsulated within a lipopolymer, which potentially results in increased antitumor immune response (PMID: 28802766, PMID: 34326131).

DrugClasses
CAS Registry Number NA
NCIT ID C49178

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Carboplatin + GEN-1 + Paclitaxel Bevacizumab Carboplatin GEN-1 Paclitaxel 0 1
Carboplatin + GEN-1 + Paclitaxel Carboplatin GEN-1 Paclitaxel 0 0
GEN-1 GEN-1 0 0
GEN-1 + Pegylated liposomal doxorubicin GEN-1 Pegylated liposomal doxorubicin 0 0


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