Drug Detail


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Drug Name RO6874281
Trade Name
Synonyms RG 7461|RG7461|Simlukafusp alfa|RO-6874281
Drug Descriptions

RO6874281 (Simlukafusp alfa) is a fusion protein consists of a human anti-fibroblast activation protein-alpha (FAP) antibody and an engineered interleukin-2, which may stimulate local immune response against FAP-positive tumor cells (NCI Drug Dictionary).

CAS Registry Number 1776942-10-9
NCIT ID C129383


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Obinutuzumab + RO6874281 Atezolizumab Bevacizumab Obinutuzumab RO6874281 0 1
Atezolizumab + Obinutuzumab + RO6874281 Atezolizumab Obinutuzumab RO6874281 0 1
Atezolizumab + RO6874281 Atezolizumab RO6874281 0 2
Cetuximab + RO6874281 Cetuximab RO6874281 0 0
Pembrolizumab + RO6874281 Pembrolizumab RO6874281 0 1
RO6874281 RO6874281 0 1

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