Drug Detail


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Drug Name LVGN6051
Trade Name
Synonyms LVGN-6051|LVGN 6051|Exlinkibart
Drug Descriptions

LVGN6051 is a monoclonal antibody that targets 4-1BB (CD137) and acts as an agonist in the presence of Fc-gammaRIIB, potentially resulting in decreased tumor growth (PMID: 31105267).

DrugClasses TNFRSF9 Antibody 30
CAS Registry Number 2642171-64-8
NCIT ID C171541


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anlotinib + LVGN6051 Anlotinib LVGN6051 0 0
Bevacizumab + Cyclophosphamide + LVGN3616 + LVGN6051 Bevacizumab Cyclophosphamide LVGN3616 LVGN6051 0 1
Bevacizumab + Cyclophosphamide + LVGN3616 + LVGN6051 + LVGN7409 Bevacizumab Cyclophosphamide LVGN3616 LVGN6051 LVGN7409 0 1
LVGN3616 + LVGN6051 + LVGN7409 + Nab-paclitaxel LVGN3616 LVGN6051 LVGN7409 Nab-paclitaxel 0 1
LVGN6051 LVGN6051 0 1
LVGN6051 + Pembrolizumab LVGN6051 Pembrolizumab 0 0

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