Drug Detail


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Drug Name AZD7648
Trade Name
Synonyms AZD-7648|AZD 7648
Drug Descriptions

AZD7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK), which potentially enhances genomic instability and sensitizes tumor cells to DNA-damaging agents (PMID: 31699977, PMID: 31851518).

DrugClasses DNA_PK Inhibitor 6
CAS Registry Number 2230820-11-6
NCIT ID C168692


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD7648 AZD7648 3 1
AZD7648 + Olaparib AZD7648 Olaparib 3 1
AZD7648 + Pegylated liposomal-doxorubicin AZD7648 Pegylated liposomal-doxorubicin 0 1
AZD7648 + Radiotherapy AZD7648 Radiotherapy 0 0

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