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|Therapy Name||Bortezomib + Fasudil|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Bortezomib||Velcade||Velcade (bortezomib) is a reversible proteasome inhibitor that inhibits survival of malignant cells and regulates bone remodeling (PMID: 26579531). Velcade (bortezomib) is FDA approved for the treatment of mantle cell lymphoma and multiple myeloma (FDA.gov).|
|Fasudil||HA-1077|AT 877||Fasudil (HA-1077) is a kinase inhibitor, especially potent against Rho-kinase, preventing downstream signaling and resulting in inhibition of cell proliferation and migration, and induction of apoptosis in cancer cells (PMID: 24908363).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|