Drug Detail


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Drug Name MGA271
Trade Name
Synonyms Enoblituzumab
Drug Descriptions

MGA271 (enoblituzumab) is an inhibitory monoclonal antibody against CD276 (B7-H3), which induces an anti-tumor immune response (PMID: 22615450).

DrugClasses CD276 Antibody 13
CAS Registry Number 1353485-38-7
NCIT ID C97510


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldesleukin + FT516 + MGA271 Aldesleukin FT516 MGA271 0 1
FT538 + MGA271 FT538 MGA271 0 1
Ipilimumab + MGA271 Ipilimumab MGA271 0 1
MGA271 MGA271 0 4
MGA271 + MGD013 MGA271 MGD013 0 1
MGA271 + Pembrolizumab MGA271 Pembrolizumab 0 1
MGA271 + Retifanlimab MGA271 Retifanlimab 0 1

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