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Drug Name U0126
Trade Name
Synonyms
Drug Descriptions

U0126 binds and inhibits Mek1 and Mek2, which may inhibit the activation of downstream signaling targets and reduce tumor cell proliferation (PMID: 9873633).

DrugClasses MEK inhibitor (Pan) 23 MEK1 Inhibitor 21 MEK2 Inhibitor 19
CAS Registry Number 1173097-76-1
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + U0126 Cetuximab U0126 0 0
Dactolisib + U0126 Dactolisib U0126 0 0
Darinaparsin + U0126 Darinaparsin U0126 0 0
Everolimus + U0126 Everolimus U0126 1 0
Torkinib + U0126 Torkinib U0126 1 0
U0126 U0126 7 0


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