Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Darinaparsin
Trade Name
Synonyms ZIO-101|ZIO101|ZIO 101|S-Dimethylarsino-Glutathione|DMAIII(SG)
Drug Descriptions

Darinaparsin is an arsenic derivative that activates MAPK signaling and inhibits Hedgehog signaling (PMID: 25381261, 25316819), and potentially leads to tumor cell killing and inhibition of tumor growth (PMID: 25381261, PMID: 25316819, PMID: 30080396).

CAS Registry Number NA
NCIT ID C61490


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Darinaparsin Darinaparsin 0 0
Darinaparsin + Docetaxel Darinaparsin Docetaxel 0 0
Darinaparsin + Selumetinib Darinaparsin Selumetinib 0 0
Darinaparsin + U0126 Darinaparsin U0126 0 0

Additional content available in CKB BOOST