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Drug Name Darinaparsin
Trade Name
Synonyms ZIO-101|ZIO101|ZIO 101|S-Dimethylarsino-Glutathione|DMAIII(SG)
Drug Descriptions

Darinaparsin is an arsenic derivative that activates MAPK signaling and inhibits Hedgehog signaling (PMID: 25381261, 25316819), and potentially leads to tumor cell killing and inhibition of tumor growth (PMID: 25381261, PMID: 25316819, PMID: 30080396).

DrugClasses
CAS Registry Number NA
NCIT ID C61490

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Darinaparsin Darinaparsin 0 0
Darinaparsin + Docetaxel Darinaparsin Docetaxel 0 0
Darinaparsin + Selumetinib Darinaparsin Selumetinib 0 0
Darinaparsin + U0126 Darinaparsin U0126 0 0


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