Drug Detail


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Drug Name Pimasertib
Trade Name
Synonyms AS703026|MSC1936369B
Drug Descriptions

Pimasertib (MSC1936369B) binds to and inhibits MEK1/2, preventing activation of downstream targets and potentially reducing tumor cell proliferation (PMID: 23587417, PMID: 31870556).

DrugClasses MEK inhibitor (Pan) 23 MEK1 Inhibitor 22 MEK2 Inhibitor 20
CAS Registry Number 1236699-92-5
NCIT ID C84864


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Therapy Name Drugs Efficacy Evidence Clinical Trials
BGB-283 + Pimasertib BGB-283 Pimasertib 1 0
Dactolisib + Pimasertib Dactolisib Pimasertib 0 0
Everolimus + Pimasertib Everolimus Pimasertib 3 0
Gemcitabine + Pimasertib Gemcitabine Pimasertib 0 0
M7824 + Pimasertib M7824 Pimasertib 0 1
Palbociclib + Pimasertib Palbociclib Pimasertib 0 0
Pimasertib Pimasertib 3 2
Pimasertib + Regorafenib Pimasertib Regorafenib 3 0
Pimasertib + SAR405838 Pimasertib SAR405838 2 0
Pimasertib + Sorafenib Pimasertib Sorafenib 3 0
Pimasertib + Voxtalisib Pimasertib Voxtalisib 0 0

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