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Drug Name | MLN2480 |
Trade Name | |
Synonyms | BIIB-024|TAK-580|MLN-2480|TAK580|DAY101|Tovorafenib |
Drug Descriptions |
MLN2480 (TAK-580) is an inhibitor of pan-Raf kinases, which interrupts RAF/MEK/ERK signal transduction pathways to inhibit tumor cell growth (PMID: 28082416, PMID: 30622172). |
DrugClasses | RAF Inhibitor (Pan) 23 |
CAS Registry Number | 1096708-71-2 |
NCIT ID | C106254 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Alisertib + MLN2480 | Alisertib MLN2480 | 0 | 1 |
MLN2480 | MLN2480 | 6 | 5 |
MLN2480 + Nivolumab | MLN2480 Nivolumab | 0 | 2 |
MLN2480 + Paclitaxel | MLN2480 Paclitaxel | 0 | 1 |
MLN2480 + Sapanisertib | MLN2480 Sapanisertib | 0 | 1 |
MLN2480 + Selumetinib | MLN2480 Selumetinib | 0 | 0 |