Drug Detail


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Drug Name Voxtalisib
Trade Name
Synonyms XL765|XL-765|SAR245409|SAR-245409
Drug Descriptions

Voxtalisib (XL765) inhibits both PI3K and mTOR kinases and results in inhibition of PI3K pathway signaling, thereby possibly leading to inhibition of cell proliferation, reduced tumor vascularization, and inhibition of tumor growth (PMID: 24634413, PMID: 31870556).

DrugClasses mTOR Inhibitor 51 PI3K Inhibitor (Pan) 40
CAS Registry Number 934493-76-2
NCIT ID C71704


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pimasertib + Voxtalisib Pimasertib Voxtalisib 0 0
Voxtalisib Voxtalisib 5 2
Voxtalisib + XL147 Voxtalisib XL147 0 0

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