Drug Detail


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Drug Name NT219
Trade Name
Synonyms NT-219|NT 219
Drug Descriptions

NT219 is a small molecule that inhibits both Stat3 and Irs1/2, resulting in decreased Stat3 phosphorylation and increased degradation of Irs1/2, and potentially leading to tumor growth inhibition (Cancer Res 2020;80(16 Suppl):Abstract nr 5639).

DrugClasses STAT3 Inhibitor 25
CAS Registry Number NA
NCIT ID C178343


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + NT219 Cetuximab NT219 0 1
NT219 NT219 0 1
NT219 + Pembrolizumab NT219 Pembrolizumab 0 0

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