Drug Detail


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Drug Name BI 882370
Trade Name
Synonyms XP-102|BI-882370|BI882370|XP 102|XP102
Drug Descriptions

BI 882370 is a Raf kinase inhibitor with potent activity against the inactive conformation of Braf and may result in tumor regression (PMID: 26916115).

DrugClasses BRAF Inhibitor 25 RAF Inhibitor (Pan) 27
CAS Registry Number 1392429-79-6
NCIT ID C187123


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + BI 882370 Afatinib BI 882370 1 0
BI 882370 BI 882370 0 1
BI 882370 + Cetuximab BI 882370 Cetuximab 1 0
BI 882370 + Trametinib BI 882370 Trametinib 2 1

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