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Drug Name LY3499446
Trade Name
Synonyms LY-3499446|LY 3499446
Drug Descriptions

LY3499446 is an oral inhibitor of KRAS G12C that prevents constitutive downstream signaling to inhibit tumor cell proliferation and growth (PMID: 32014824).

DrugClasses KRAS G12C inhibitor 28
CAS Registry Number NA
NCIT ID C166410

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + LY3499446 Abemaciclib LY3499446 0 1
Cetuximab + LY3499446 Cetuximab LY3499446 0 1
Erlotinib + LY3499446 Erlotinib LY3499446 0 1
LY3499446 LY3499446 0 1


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