Drug Detail


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Drug Name Savolitinib
Trade Name
Synonyms HMPL-504|AZD6094|AZD-6094|Volitinib
Drug Descriptions

Savolitinib (AZD6094) is a selective MET inhibitor, which inhibits MET kinase activity, resulting in decreased downstream signaling, and may inhibit growth of MET-expressing tumors (PMID: 25248999, PMID: 32027846, PMID: 30952639).

DrugClasses MET Inhibitor 59
CAS Registry Number 1313725-88-0
NCIT ID C104732


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Savolitinib Afatinib Savolitinib 0 0
Cetuximab + Savolitinib Cetuximab Savolitinib 0 1
Durvalumab + Savolitinib Durvalumab Savolitinib 0 1
Furmonertinib + Savolitinib Furmonertinib Savolitinib 0 0
Gefitinib + Savolitinib Gefitinib Savolitinib 0 0
Itraconazole + Savolitinib Itraconazole Savolitinib 0 0
Lorlatinib + Savolitinib Lorlatinib Savolitinib 0 0
Moxifloxacin + Savolitinib Moxifloxacin Savolitinib 0 0
Osimertinib + Savolitinib Osimertinib Savolitinib 0 5
Savolitinib Savolitinib 0 7

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