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Drug Name Ezabenlimab
Trade Name
Synonyms BI754091|BI-754091|BI 754091
Drug Descriptions

Ezabenlimab (BI 754091) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (J Clin Oncol. 36, no. 5_suppl (February 2018) 212-212).

DrugClasses Immune Checkpoint Inhibitor 151 PD-L1/PD-1 antibody 98
CAS Registry Number 2249882-54-8
NCIT ID C132252

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ATP128 + Ezabenlimab ATP128 Ezabenlimab 0 1
ATP128 + Ezabenlimab + VSV-GP128 ATP128 Ezabenlimab VSV-GP128 0 1
BI 1387446 + Ezabenlimab BI 1387446 Ezabenlimab 0 1
BI 1831169 + Ezabenlimab BI 1831169 Ezabenlimab 0 1
BI 765049 + Ezabenlimab BI 765049 Ezabenlimab 0 1
BI 765179 + Ezabenlimab BI 765179 Ezabenlimab 0 1
BI 770371 + Ezabenlimab BI 770371 Ezabenlimab 0 1
BI 836880 + Effi-DEM + Ezabenlimab BI 836880 Effi-DEM Ezabenlimab 0 1
BI 836880 + Ezabenlimab BI 836880 Ezabenlimab 0 1
BI 891065 + Ezabenlimab BI 891065 Ezabenlimab 0 1
BI 907828 + Ezabenlimab BI 907828 Ezabenlimab 1 1
BI 907828 + Ezabenlimab + Miptenalimab BI 907828 Ezabenlimab Miptenalimab 0 1
Cetuximab + Effi-DEM + Ezabenlimab Cetuximab Effi-DEM Ezabenlimab 0 1
Effi-DEM + Ezabenlimab Effi-DEM Ezabenlimab 0 3
Ezabenlimab Ezabenlimab 0 3
Ezabenlimab + Miptenalimab Ezabenlimab Miptenalimab 0 0
Ezabenlimab + NK-92/5.28.z Ezabenlimab NK-92/5.28.z 0 1


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