Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name BI 754091
Trade Name
Synonyms BI754091|BI-754091|Ezabenlimab
Drug Descriptions

BI 754091 (Ezabenlimab) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (J Clin Oncol. 36, no. 5_suppl (February 2018) 212-212).

DrugClasses Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 89
CAS Registry Number 2249882-54-8
NCIT ID C132252

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ATP128 + BI 754091 ATP128 BI 754091 0 1
ATP128 + BI 754091 + VSV-GP128 ATP128 BI 754091 VSV-GP128 0 1
BI 1387446 + BI 754091 BI 1387446 BI 754091 0 1
BI 1831169 + BI 754091 BI 1831169 BI 754091 0 1
BI 754091 BI 754091 0 3
BI 754091 + BI 754111 BI 754091 BI 754111 0 0
BI 754091 + BI 754111 + BI 907828 BI 754091 BI 754111 BI 907828 0 1
BI 754091 + BI 765049 BI 754091 BI 765049 0 1
BI 754091 + BI 765179 BI 754091 BI 765179 0 1
BI 754091 + BI 770371 BI 754091 BI 770371 0 1
BI 754091 + BI 836880 BI 754091 BI 836880 0 1
BI 754091 + BI 836880 + Effi-DEM BI 754091 BI 836880 Effi-DEM 0 1
BI 754091 + BI 891065 BI 754091 BI 891065 0 1
BI 754091 + BI 907828 BI 754091 BI 907828 0 1
BI 754091 + Cetuximab + Effi-DEM BI 754091 Cetuximab Effi-DEM 0 1
BI 754091 + Effi-DEM BI 754091 Effi-DEM 0 2


Additional content available in CKB BOOST