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Therapy Name | BI 754091 + BI 765049 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
BI 754091 | BI754091|BI-754091|Ezabenlimab | Immune Checkpoint Inhibitor 141 PD-L1/PD-1 antibody 83 | BI 754091 (Ezabenlimab) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (J Clin Oncol. 36, no. 5_suppl (February 2018) 212-212). | |
BI 765049 | BI-765049|BI765049 | Limited information is currently available on BI 765049 (Mar 2022). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04752215 | Phase I | BI 754091 + BI 765049 BI 765049 | A Study Evaluating Different Doses of BI 765049 When Given Alone and When Given With BI 754091 to Patients With Advanced Solid Tumors Having the B7-H6 Marker | Recruiting | USA | 0 |