Drug Detail


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Drug Name PF-07284892
Trade Name
Synonyms PF 07284892|PF07284892|ARRY-558|ARRY 558|ARRY558
Drug Descriptions

PF-07284892 is a small molecule inhibitor of SHP2 that may block MAPK signaling and lead to tumor growth inhibition (NCI Thesaurus).

DrugClasses SHP2 Inhibitor 16
CAS Registry Number NA
NCIT ID C178469


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Binimetinib + PF-07284892 Binimetinib PF-07284892 0 1
Cetuximab + Encorafenib + PF-07284892 Cetuximab Encorafenib PF-07284892 0 1
Lorlatinib + PF-07284892 Lorlatinib PF-07284892 0 1
PF-07284892 PF-07284892 0 1

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