Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name INCAGN01949
Trade Name
Synonyms INCAGN1949|INCAGN 1949|INCAGN-1949
Drug Descriptions

INCAGN01949 is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (Cancer Res 2016;76(14 Suppl):Abstract nr 3204).

DrugClasses OX40 Antibody 12
CAS Registry Number NA
NCIT ID C129967


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
INCAGN01949 INCAGN01949 0 1
INCAGN01949 + Ipilimumab INCAGN01949 Ipilimumab 0 1
INCAGN01949 + Ipilimumab + Nivolumab INCAGN01949 Ipilimumab Nivolumab 0 1
INCAGN01949 + Nivolumab INCAGN01949 Nivolumab 0 1
INCAGN01949 + Vidutolimod INCAGN01949 Vidutolimod 0 1

Additional content available in CKB BOOST