Drug Detail


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Drug Name INCB106385
Trade Name
Synonyms INCB-106385|INCB 106385
Drug Descriptions

INCB106385 is a dual inhibitor of A2A and A2B receptors, which may prevent immune suppression in the tumor microenvironment and promote anti-tumor immune response (AACR Annual Meeting Apr 2020, Session PO.IM02.03, Abstract # LB157).

DrugClasses Adenosine Targeting 22
CAS Registry Number NA
NCIT ID C178440


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Therapy Name Drugs Efficacy Evidence Clinical Trials
INCA00186 + INCB106385 INCA00186 INCB106385 0 1
INCA00186 + INCB106385 + Retifanlimab INCA00186 INCB106385 Retifanlimab 0 1
INCB106385 INCB106385 0 1
INCB106385 + Retifanlimab INCB106385 Retifanlimab 0 1

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