Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name INCB106385
Trade Name
Synonyms INCB-106385|INCB 106385
Drug Descriptions

INCB106385 is a dual inhibitor of A2A and A2B receptors, which may prevent immune suppression in the tumor microenvironment and promote anti-tumor immune response (AACR Annual Meeting Apr 2020, Session PO.IM02.03, Abstract # LB157).

DrugClasses Adenosine Targeting 23
CAS Registry Number NA
NCIT ID C178440

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
INCA00186 + INCB106385 INCA00186 INCB106385 0 1
INCA00186 + INCB106385 + Retifanlimab INCA00186 INCB106385 Retifanlimab 0 1
INCB106385 INCB106385 0 1
INCB106385 + Retifanlimab INCB106385 Retifanlimab 0 1


Additional content available in CKB BOOST