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Therapy Name | BGB-30813 + Tislelizumab |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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BGB-30813 | BGB 30813|BGB30813 | DGKZ Inhibitor 3 | Limited information is currently available on BGB-30813, a putative DGKzeta inhibitor (Jun 2023). | |
Tislelizumab | BGB-A317 | Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 112 | Tislelizumab (BGB-A317) is a human monoclonal antibody that targets PD-1 (PDCD1), thereby blocking the binding of PD-L1 (CD274) and potentially resulting in activation of a T-cell immune response against tumor cells (PMID: 32769013, PMID: 32561638, PMID: 32540858). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05904496 | Phase I | BGB-30813 BGB-30813 + Tislelizumab | A Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BGB-30813 | Recruiting | USA | ESP | AUS | 0 |