Drug Detail

Drug Name Toca 511
Trade Name
Synonyms T5.0002
Drug Descriptions

Toca 511 is a retroviral vector encoding yeast cytosine deaminase, which converts the prodrug flucytosine into 5-fluorouracil upon infection of tumor cells, leading to tumor cell death (PMID: 22547150).

DrugClasses Chemotherapy - Antimetabolite 10


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Toca 511 Toca 511 0 1
Toca 511 + Toca FC Toca 511 Toca FC 2 3

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