Drug Detail


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Drug Name AZD5991
Trade Name
Synonyms AZD-5991|AZD 5991
Drug Descriptions

AZD5991 binds to and inhibits Mcl1, potentially resulting in increased tumor cell apoptosis and decreased tumor growth (Cancer Res July 1 2017 (77) (13 Supplement) DDT01-02, PMID: 32204955).

DrugClasses MCL1 Inhibitor 18
CAS Registry Number 2143010-83-5
NCIT ID C137989


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD4320 + AZD5991 AZD4320 AZD5991 0 0
AZD5991 AZD5991 1 1
AZD5991 + AZD8186 AZD5991 AZD8186 1 0
AZD5991 + Capivasertib AZD5991 Capivasertib 1 0
AZD5991 + Ruxolitinib AZD5991 Ruxolitinib 0 0
AZD5991 + Selumetinib AZD5991 Selumetinib 1 0
AZD5991 + Temozolomide AZD5991 Temozolomide 1 0
AZD5991 + Trametinib AZD5991 Trametinib 1 0

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