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Genasense (oblimersen) is an antisense oligonucleotide that targets BCL-2, resulting in decreased protein expression, which potentially leads to increased tumor cell apoptosis (PMID: 24667300).
|DrugClasses||BCL2 inhibitor 17|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Nab-paclitaxel + Oblimersen + Temozolomide||Nab-paclitaxel Oblimersen Temozolomide||1||0|