Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name E7016
Trade Name
Synonyms E-7016
Drug Descriptions

E7016 is an inhibitor of PARP1 and PARP2, which results in the accumulation of DNA damage, thereby potentially resulting in increased tumor cell death and increased sensitivity to DNA damaging agents (Mol Cancer Ther 2011;10(11 Suppl):Abstract nr B185, PMID: 19147766).

DrugClasses PARP Inhibitor (Pan) 30
CAS Registry Number 902128-92-1
NCIT ID C91387


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
E7016 E7016 0 0
E7016 + Temozolomide E7016 Temozolomide 0 0

Additional content available in CKB BOOST