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Drug Name NT-I7
Trade Name
Synonyms GX-I7|rhIL-7-hyFc|IL-7-hyFc|Efineptakin alfa|Hyleukin
Drug Descriptions

NT-I7 is a fusion protein comprised of a recombinant interleukin-7 (IL-7) linked to a hybrid immunoglobulin Fc region, which potentially has increased stability and enhances anti-tumor immune response (Journal of Clinical Oncology 37, no. 15_suppl, Abs nr: e13516).

CAS Registry Number 2026634-47-7
NCIT ID C151927


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + NT-I7 Atezolizumab NT-I7 0 2
Dexamethasone + NT-I7 Dexamethasone NT-I7 0 1
Nivolumab + NT-I7 NT-I7 Nivolumab 0 1
NT-I7 NT-I7 0 3
NT-I7 + Pembrolizumab NT-I7 Pembrolizumab 0 2
NT-I7 + Radiotherapy + Temozolomide NT-I7 Radiotherapy Temozolomide 0 1

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