Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name NT-I7
Trade Name
Synonyms GX-I7|rhIL-7-hyFc|IL-7-hyFc|Efineptakin alfa|Hyleukin
Drug Descriptions

NT-I7 is a fusion protein comprised of a recombinant interleukin-7 (IL-7) linked to a hybrid immunoglobulin Fc region, which potentially has increased stability and enhances anti-tumor immune response (Journal of Clinical Oncology 37, no. 15_suppl, Abs nr: e13516).

CAS Registry Number 2026634-47-7
NCIT ID C151927


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + NT-I7 Atezolizumab NT-I7 0 2
Dexamethasone + NT-I7 Dexamethasone NT-I7 0 1
Nivolumab + NT-I7 NT-I7 Nivolumab 0 1
NT-I7 NT-I7 0 3
NT-I7 + Pembrolizumab NT-I7 Pembrolizumab 0 2
NT-I7 + Radiotherapy + Temozolomide NT-I7 Radiotherapy Temozolomide 0 1

Additional content available in CKB BOOST