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|Synonyms||CC 90010|CC90010|BMS-986378|BMS 986378|BMS986378|
CC-90010 is a reversible, small molecule drug that binds to BD2 (bromodomain 2) of BET proteins and inhibits interaction with acetylated histones, potentially resulting in disrupted expression of genes that promote cell growth, and inhibition of proliferation of tumor cells overexpressing BET proteins (PMID: 32240793).
|DrugClasses||BET Inhibitor (Pan) 32|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|CC-90010 + Temozolomide||CC-90010 Temozolomide||0||1|