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Drug Name CC-90010
Trade Name
Synonyms CC 90010|CC90010|BMS-986378|BMS 986378|BMS986378
Drug Descriptions

CC-90010 is a reversible, small molecule drug that binds to BD2 (bromodomain 2) of BET proteins and inhibits interaction with acetylated histones, potentially resulting in disrupted expression of genes that promote cell growth, and inhibition of proliferation of tumor cells overexpressing BET proteins (PMID: 32240793).

DrugClasses BET Inhibitor (Pan) 32
CAS Registry Number NA
NCIT ID C151951


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Therapy Name Drugs Efficacy Evidence Clinical Trials
CC-90010 CC-90010 0 3
CC-90010 + Temozolomide CC-90010 Temozolomide 0 1
CC-90010 + Vinorelbine CC-90010 Vinorelbine 0 1

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