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|Therapy Name||BMX-001 + Temozolomide|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|BMX-001||BMX-001 is a human mitochondrial manganese superoxide dismutase (MnSOD) mimetic that clears reactive oxygen species upon cellular internalization, thereby potentially reducing the degree of chemotoxicity within healthy tissue (NCI Drug Dictionary).|
|Temozolomide||Temodar||Methazolastone||Chemotherapy - Alkylating 14||Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT02655601||Phase Ib/II||BMX-001 + Temozolomide Temozolomide||Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001||Recruiting|