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Drug Name STA-8666
Trade Name
Synonyms PEN-866|PEN866|STA-12-8666
Drug Descriptions

STA-8666 is a molecule that targets active HSP90 and is linked to the active metabolite of Camptosar (irinotecan), SN38, which may result in antitumor activity including tumor stabilization and regression (PMID: 27267850, PMID: 27608846, PMID: 28453558).

DrugClasses HSP90 Inhibitor 35
CAS Registry Number 1472614-83-7
NCIT ID C151953


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + STA-8666 Carboplatin STA-8666 0 0
STA-8666 STA-8666 0 1
STA-8666 + Temozolomide + Vincristine Sulfate STA-8666 Temozolomide Vincristine Sulfate 0 1

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