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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|WM-8014||MOZ-IN-3||WM-8014 selectively inhibits KAT6A and KAT6B, which potentially results in induction of cellular senescence and inhibition of tumor cell proliferation (PMID: 30069049).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|HRAS G12V||Advanced Solid Tumor||sensitive||WM-8014||Preclinical||Actionable||In a preclinical study, WM-8014 inhibited proliferation of a transformed mouse cell line expressing HRAS G12V in culture, and inhibited proliferation and induced senescence in a transgenic zebrafish model (PMID: 30069049).||30069049|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|