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Therapy Name | PRT811 |
Synonyms | |
Therapy Description |
PRT811 inhibits PRMT5, which blocks protein symmetric arginine dimethylation, potentially leading to decreased tumor growth (Mol Cancer Ther (2021) 20 (12_Supplement): P044). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
PRT811 | PRT 811|PRT-811 | PRMT5 Inhibitor 16 | PRT811 inhibits PRMT5, which blocks protein symmetric arginine dimethylation, potentially leading to decreased tumor growth (Mol Cancer Ther (2021) 20 (12_Supplement): P044). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04089449 | Phase I | PRT811 | A Study of PRT811 in Participants With Advanced Solid Tumors, Gliomas and Myelofibrosis | Completed | USA | 0 |