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Molecular Profile | RET M918T |
Therapy | FHND5071 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
RET M918T | Advanced Solid Tumor | predicted - sensitive | FHND5071 | Preclinical - Cell culture | Actionable | In a preclinical study, FHND5071 inhibited Ret phosphorylation and proliferation in cells expressing RET M918T in culture (Cancer Res (2023) 83 (8_Supplement): LB330). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
Abstract LB330: FHND5071: a selective RET inhibitor with unique pharmacokinetic profile | Full reference... |