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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SAR441000||SAR 441000|SAR-441000|BNT 131|BNT131|BNT-131||SAR441000 is a mixture of mRNA encoding IL-12sc, IL-15sushi, IFNa and GM-CSF that when taken up by cells is translated and released into the tumor microenvironment, potentially resulting in immune system activation and antitumor immune response (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT03871348||Phase I||SAR441000 Cemiplimab + SAR441000||A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors||Recruiting|