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Therapy Name | HMPL-306 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
HMPL-306 | HMPL 306|HMPL306 | IDH Inhibitor (Pan) 3 | HMPL-306 specifically inhibits mutant IDH1/2, resulting in decreased conversion of alpha-ketoglutarate into 2-hydroxyglutarate, and potentially leading to inhibition of of IDH1/2 mutant tumor cell proliferation (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT04762602 | Phase I | HMPL-306 | A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations | Recruiting | USA | ESP | 0 |
NCT04764474 | Phase I | HMPL-306 | A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH | Recruiting | USA | ESP | 0 |