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Therapy Name THOR-707 + unspecified CTLA4 antibody
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
THOR-707 THOR707|THOR 707 THOR-707 is a pegylated recombinant version of IL-2 that binds IL2beta, but does not bind to IL-2 alpha, potentially resulting in activation and tumor infiltration of CD8-positive T cells without proliferation of CD4-positive immune cells (Annals of Oncology (2019) 30 (suppl_5): v475-v532).
unspecified CTLA4 antibody experimental CTLA4 antibody

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT04009681 Phase Ib/II THOR-707 + unspecified PD-L1 antibody THOR-707 + unspecified PD-1 antibody THOR-707 THOR-707 + unspecified CTLA4 antibody A Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors (THOR-707-101) Recruiting


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