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Therapy Name | ER-851 |
Synonyms | |
Therapy Description |
ER-851 selectively inhibits AXL, potentially leading to decreased cell viability and reduced of tumor growth (PMID: 36279567). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
ER-851 | ER-001259851-000|ER851|ER 851 | AXL Inhibitor 30 | ER-851 selectively inhibits AXL, potentially leading to decreased cell viability and reduced of tumor growth (PMID: 36279567). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
AXL positive | Advanced Solid Tumor | sensitive | ER-851 | Preclinical - Cell culture | Actionable | In a preclinical study, ER-851 decreased viability of transformed cells expressing AXL in culture, and inhibited tumor growth in a cell line xenograft model (PMID: 36279567). | 36279567 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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