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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|DKN-01||DKN 01|DKN01||WNT Inhibitor 13||DKN-01 is a monoclonal antibody that binds to and inhibits Dkk1, a Wnt receptor antagonist, resulting in restoration of Wnt signaling and tumor growth inhibition (PMID: 28731148, PMID: 32192732).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT04681248||Expanded access||DKN-01||Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors||Available||USA||0|
|NCT03395080||Phase II||DKN-01 DKN-01 + Paclitaxel||A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Relapsed/ Refractory Endometrioid Endometrial or Endometrioid Ovarian Cancer (P204) (P204)||Completed||USA||0|
|NCT03837353||Phase Ib/II||DKN-01 DKN-01 + Docetaxel||A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1||Recruiting||USA||0|