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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SEL120-34A||SEL120|SEL 120-34||CDK8 Inhibitor 3||SEL120-34A selectively inhibits CDK8, resulting in decreased STAT5 and STAT1 phosphorylation and downstream signaling, and potentially leading to reduced tumor cell growth (PMID: 28422713).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT04021368||Phase I||SEL120-34A||SEL120 in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome||Recruiting|